CD10 Antibody (DA012)
CD10 Antibody (DA012)
Recombinant monoclonal mouse antibody
Description
CD10, common acute lymphoblastic leukemia antigen, is expressed by a subset of T follicular helper cells.1,2 CD10 has a direct role in cell growth and apoptosis and has been implicated in tumor cells proliferation.3 CD10 expression has been reported in a variety of tissues; including renal cell carcinoma, hepatocellular carcinoma, and follicular lymphoma.4, 5
References
1. Maguer-Satta V, et al. Concise review: neutral endopeptidase (CD10): a multifaceted environment actor in stem cells, physiological mechanisms, and cancer. Stem Cells. 2011; 29:389-96.
2. Laurent C, et al. A novel subset of T-helper cells: follicular T-helper cells and their markers. Haematologica. 2010; 95: 356-8.
3. Onak NK, et al. CD10 expression in urothelial bladder carcinomas: staining patterns and relationship with pathologic parameters. Turk J Med Sci. 2010; 40:177-84.
4. Chu P, et al. Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Am J Clin Pathol. 2000; 113: 374-82.
5. Swerdlow S, et al. WHO classification of tumours of hematopoietic and lymphoid tissues. 4th edition. 2008. P. 220,233,255,265,309.
2. Laurent C, et al. A novel subset of T-helper cells: follicular T-helper cells and their markers. Haematologica. 2010; 95: 356-8.
3. Onak NK, et al. CD10 expression in urothelial bladder carcinomas: staining patterns and relationship with pathologic parameters. Turk J Med Sci. 2010; 40:177-84.
4. Chu P, et al. Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Am J Clin Pathol. 2000; 113: 374-82.
5. Swerdlow S, et al. WHO classification of tumours of hematopoietic and lymphoid tissues. 4th edition. 2008. P. 220,233,255,265,309.
Specifications
Application:
IHC (FFPE)
Host:
Mouse
Subclass:
IgG2a/κ
Immunogen:
Synthetic peptide of human CD10
Cellular location:
Cell membrane
Control:
Tonsil
Order information
| RMA1A002 | Concentrate | IVD(R) |
| RMA1A002 | 10 ml Ready to use | IVD(R) |
| RMA1A002 | 6 ml Ready to use | IVD(R) |
| RMA1A002 | 3 ml Ready to use | IVD(R) |
