CD34 Antibody (DA022)
CD34 Antibody (DA022)
Recombinant monoclonal rabbit antibody
Description
CD34 is a cell surface glycophosphoprotein expressed on human hematopoietic progenitor cells and can be used for identifying blast cells.1 CD34 is a marker for vascular endothelial cells and has been shown in literature to be highly sensitive for angiosarcomas and Kaposi's sarcomas.2 In addition, CD34 is expressed in soft tissue tumors such as gastrointestinal stromal tumors (GIST).3 It is also used to differentiate Isolated fibrous tumors, dermatofibrosarcoma protuberans and Malignant phyllodes tumor of the breast.
References
1. Torlakovic G, et al. CD34/QBEND10 immunostaining in the bone marrow trephine biopsy: a study of CD34-positive mononuclear cells and megakaryocytes. Arch Pathol Lab Med. 2002; 126:823-8.
2. Nielsen JS, et al. Novel functions of the CD34 family. J Cell Sci. 2008; 121: 3683-92.
3. Kisluk J, et al. Immunohistochemical diagnosis of gastrointestinal stromal tumors - an analysis of 80 cases from 2004 to 2010. Adv. Clin Exp Med. 2013; 22:33-9.
2. Nielsen JS, et al. Novel functions of the CD34 family. J Cell Sci. 2008; 121: 3683-92.
3. Kisluk J, et al. Immunohistochemical diagnosis of gastrointestinal stromal tumors - an analysis of 80 cases from 2004 to 2010. Adv. Clin Exp Med. 2013; 22:33-9.
Specifications
Application:
IHC (FFPE)
Host:
Rabbit
Subclass:
IgG
Immunogen:
Synthetic peptide of human CD34
Cellular location:
Cell membrane
Control:
Appendix
Order information
| RMA1A006 | Concentrate | IVD(R) |
| RMA1A006 | 10 ml Ready to use | IVD(R) |
| RMA1A006 | 6 ml Ready to use | IVD(R) |
| RMA1A006 | 3 ml Ready to use | IVD(R) |
