Thyroglobulin Antibody (DA111)
Thyroglobulin Antibody (DA111)
Recombinant monoclonal rabbit antibody
Description
Thyroglobulin (Tg) is the precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).1 Tg is a high molecular weight glycoprotein found in normal thyroid follicular cells.1,2 Thyroglobulin is useful for identifying thyroid carcinoma of papillary and follicular types and for identifying tumors of thyroid origin when working with adenocarcinoma of unknown primary.2-5
References
1. Sellitti DF, et al. Intrinsic regulation of thyroid function by thyroglobulin. Thyroid. 2014; 24:625-38.
2. Bellet D, et al. Production and in vitro utilization of monoclonal antibodies to human thyroglobulin. J Clin Endocrinol Metab. 1983; 56:530-3.
3. Bejarano PA, et al. Thyroid transcription factor-1, thyroglobulin, cytokeratin 7, and cytokeratin 20 in thyroid neoplasms. Appl Immunohistochem Mol Morphol. 2000; 8:189-94.
4. Judkins AR, et al. Utility of immunohistochemistry in the evaluation of necrotic thyroid tumors. Hum Pathol. 1999; 30:1373-6.
5. Hammer SP. Metastatic adenocarcinoma of unknown primary origin. Hum Pathol. 1998; 29:1393-402.
2. Bellet D, et al. Production and in vitro utilization of monoclonal antibodies to human thyroglobulin. J Clin Endocrinol Metab. 1983; 56:530-3.
3. Bejarano PA, et al. Thyroid transcription factor-1, thyroglobulin, cytokeratin 7, and cytokeratin 20 in thyroid neoplasms. Appl Immunohistochem Mol Morphol. 2000; 8:189-94.
4. Judkins AR, et al. Utility of immunohistochemistry in the evaluation of necrotic thyroid tumors. Hum Pathol. 1999; 30:1373-6.
5. Hammer SP. Metastatic adenocarcinoma of unknown primary origin. Hum Pathol. 1998; 29:1393-402.
Specifications
Application:
IHC (FFPE)
Host:
Rabbit
Subclass:
IgG
Immunogen:
Synthetic peptide of human Thyroglobulin
Cellular location:
Nucleus
Control:
Normal Thyroid
Order information
| RMA1A031 | Concentrate | IVD(R) |
| RMA1A031 | 10 ml Ready to use | IVD(R) |
| RMA1A031 | 6 ml Ready to use | IVD(R) |
| RMA1A031 | 3 ml Ready to use | IVD(R) |
