CD5 Antibody (DA029)
CD5 Antibody (DA029)
Recombinant monoclonal mouse antibody
Description
CD5 is a glycoprotein monomer with an MW of 67 kDa belonging to the scavenger receptor cysteine-rich (SRCR) family of extracellular domain-like structures. It possesses a large cytoplasmic domain suitable for signal transduction.
CD5 is a T-cell marker that also reacts with a range of neoplastic B cells, e.g., B-cell Chronic Lymphocytic Leukemia (B-CLL), B-cell Small Lymphocytic Lymphoma (B-SLL), and Mantle Cell Lymphoma. CD5 is expressed in T-lymphocyte subsets and is modulated during cellular activation; however, it does not react with granulocytes or monocytes. 1-4
References
1. Chan JKC, et al. Histopathology. 1994;25:517-536
2. Kasaian MT, et al. Proc of the Soc for Exp Bio and Med. 1991;197:226-
241
3. Jones NH, et al. Nature. 1986;323:346-349
4. U.S. Department of Health and Human Services: Centers for Disease Control and Prevention. Guidelines for Safe Work Practices in Human and Animal Medical Diagnostic Laboratories. Supplement/Vol. 61, January 6, 2012.
https://www.cdc.gov/mmwr/pdf/other/su6101.pdf
2. Kasaian MT, et al. Proc of the Soc for Exp Bio and Med. 1991;197:226-
241
3. Jones NH, et al. Nature. 1986;323:346-349
4. U.S. Department of Health and Human Services: Centers for Disease Control and Prevention. Guidelines for Safe Work Practices in Human and Animal Medical Diagnostic Laboratories. Supplement/Vol. 61, January 6, 2012.
https://www.cdc.gov/mmwr/pdf/other/su6101.pdf
Specifications
Application:
IHC (FFPE)
Host:
Mouse
Subclass:
IgG2a/κ
Immunogen:
Synthetic peptide of human CD5
Cellular location:
Cell membrane
Control:
Tonsil
Order information
| RMF1A059 | Concentrate | IVD(R) |
| RMF1A059 | 10 ml Ready to use | IVD(R) |
| RMF1A059 | 6 ml Ready to use | IVD(R) |
| RMF1A059 | 3 ml Ready to use | IVD(R) |
