EGFR Antibody (DA054)
EGFR Antibody (DA054)
Recombinant monoclonal rabbit antibody
Description
Epidermal Growth Factor Receptor (EGFR) is the receptor for epidermal growth factor (EGF). It is a member of the ErbB family receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER-2 neu (ErbB-2), HER-3 (ErbB-3) and HER-4 (ErbB-4). 1-4
Ninety percent of EGFR mutations in lung adenocarcinoma occur with the L858R mutation in exon 21 and the E764-A705del deletion in exon 19.EGFR(SP111) can be used to screen lung adenocarcinoma cases with E764-A705del deletion.
References
1. Cohen S, et al. J Biol Chem. 1982;257:1523
2. Ozane B, et al. J Pathol. 1986; 149:191
3. Niikura H, et al. Human Pathol. 1996; 27:282
4. U.S. Department of Health and Human Services: Centers for Disease Control and Prevention. Guidelines for Safe Work Practices in Human and Animal Medical Diagnostic Laboratories. Supplement / Vol. 61, January 6, 2012.
https://www.cdc.gov/mmwr/pdf/other/su6101.pdf
2. Ozane B, et al. J Pathol. 1986; 149:191
3. Niikura H, et al. Human Pathol. 1996; 27:282
4. U.S. Department of Health and Human Services: Centers for Disease Control and Prevention. Guidelines for Safe Work Practices in Human and Animal Medical Diagnostic Laboratories. Supplement / Vol. 61, January 6, 2012.
https://www.cdc.gov/mmwr/pdf/other/su6101.pdf
Specifications
Application:
IHC (FFPE)
Host:
Rabbit
Subclass:
IgG
Immunogen:
Synthetic peptide from human EGFR
Cellular location:
Cytoplasm/Cell membrane
Control:
Tonsil
Order information
| RMF1A066 | Concentrate | IVD(R) |
| RMF1A066 | 10 ml Ready to use | IVD(R) |
| RMF1A066 | 6 ml Ready to use | IVD(R) |
| RMF1A066 | 3 ml Ready to use | IVD(R) |
