Mesothelial Cell Antibody (DA079)
Mesothelial Cell Antibody (DA079)
Recombinant monoclonal mouse antibody
Description
Mesothelial Cell, also Hector Battifora mesothelial-1 (HBME-1), is a membrane antigen that exists in the microvilli of mesothelial cells and other epithelial cells.1 Anti-HBME-1 labels thyroid papillary carcinoma and follicular carcinoma but not normal thyroid making it a valuable marker for distinguishing thyroid malignacies from benign thyroid lesions.2 It has also been demonstrated to label mesothelial cells, both benign and malignant (malignant mesothelioma) and thus can aid in the identification of mesothelioma.2
References
1. Cheung CC, et al. Immunohistochemical diagnosis of papillary thyroid carcinoma. Mod Pathol. 2001; 14:338-42
2. Bateman AC, et al. Immunohistochemical phenotype of malignant mesothelioma: predictive value of CA125 and HBME-1 expression. Histopathology. 1997; 30:49-56.
2. Bateman AC, et al. Immunohistochemical phenotype of malignant mesothelioma: predictive value of CA125 and HBME-1 expression. Histopathology. 1997; 30:49-56.
Specifications
Application:
IHC (FFPE)
Host:
Mouse
Subclass:
Immunogen:
Cellular location:
Cell membrane
Control:
Order information
| MMB1A098 | Concentrate | IVD(R) |
| MMB1A098 | 10 ml Ready to use | IVD(R) |
| MMB1A098 | 6 ml Ready to use | IVD(R) |
| MMB1A098 | 3 ml Ready to use | IVD(R) |
