SALL4 Antibody (DA106)
SALL4 Antibody (DA106)
Recombinant monoclonal mouse antibody
Description
Sal-like protein 4 (SALL4) is a zinc-finger transcription factor1 that serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities.2 SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors and teratomas.1 SALL4 expression is also seen in the spermatogonia of normal testis.
References
1. Miettinen M, et al. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014; 38:410-20.
2. Yang J, et al. Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells. PNAS. 2008; 105:19756-61.
2. Yang J, et al. Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells. PNAS. 2008; 105:19756-61.
Specifications
Application:
IHC (FFPE)
Host:
Mouse
Subclass:
IgG1/κ
Immunogen:
Synthetic peptide of human SALL4
Cellular location:
Nucleus
Control:
Seminoma
Order information
| MMB1A103 | Concentrate | IVD(R) |
| MMB1A103 | 10 ml Ready to use | IVD(R) |
| MMB1A103 | 6 ml Ready to use | IVD(R) |
| MMB1A103 | 3 ml Ready to use | IVD(R) |
