CA19-9 Antibody (DA122)
CA19-9 Antibody (DA122)
Recombinant monoclonal mouse antibody
Description
Carbohydrate Antigen 19-9 (CA19-9) is a sialylated Lewis A blood group antigen.1 It is synthesized by glycosyltransferases and has been identified as a component of gangliosides, glycoproteins and mucins.1,2 Anti-CA19-9 reacts with epithelial cells of normal pancreas, stomach, and colon as well as various adenocarcinomas, including pancreatic, gastric, and colorectal adenocarcinomas.3,4
References
1. Wu E, et al. CA 19-9 and Pancreatic Cancer. Clin Adv Hematol Oncol. 2013; 11:53-5.
2. Partyka K, et al. Diverse monoclonal antibodies against the CA 19-9 antigen show variation in binding specificity with consequences for clinical interpretation. Proteomics. 2012; 12:2212-20.
3. Remmers N, et al. Aberrant expression of mucin core proteins and O-linked glycans associated with progression of pancreatic cancer. Clin Cancer Res. 2013; 19:1981-93.
4. Terada T. An immunohistochemical study of primary signet-ring cell carcinoma of the stomach and colorectum: III expressions of EMA, CEA, CA19-9, CDX-2, p53, Ki-67 antigen, TTF-1, vimentin, and p63 in normal mucosa and in 42 cases. Int J Clin Exp Pathol. 2013; 6:630-8.
2. Partyka K, et al. Diverse monoclonal antibodies against the CA 19-9 antigen show variation in binding specificity with consequences for clinical interpretation. Proteomics. 2012; 12:2212-20.
3. Remmers N, et al. Aberrant expression of mucin core proteins and O-linked glycans associated with progression of pancreatic cancer. Clin Cancer Res. 2013; 19:1981-93.
4. Terada T. An immunohistochemical study of primary signet-ring cell carcinoma of the stomach and colorectum: III expressions of EMA, CEA, CA19-9, CDX-2, p53, Ki-67 antigen, TTF-1, vimentin, and p63 in normal mucosa and in 42 cases. Int J Clin Exp Pathol. 2013; 6:630-8.
Specifications
Application:
IHC (FFPE)
Host:
Mouse
Subclass:
IgM/κ
Immunogen:
Synthetic peptide of human CA 19-9
Cellular location:
Cytoplasm
Control:
Colon Carcinoma
Order information
| DMRDB139 | Concentrate | IVD(R) |
| DMRDB139 | 10 ml Ready to use | IVD(R) |
| DMRDB139 | 6 ml Ready to use | IVD(R) |
| DMRDB139 | 3 ml Ready to use | IVD(R) |
